微软文档：
How to disable the Autorun functionality in Windows
方法一，通过组策略设置（注意：Windows XP HOME不支持）：

How to use Group Policy settings to disable all Autorun features in Windows Server 2003, Windows XP Professional, and Windows 2000

1. Click Start, click Run, type Gpedit.msc in the Open box, and then click OK.
2. Under Computer Configuration, expand Administrative Templates, and then click System.
3. In the Settings pane, right-click Turn off Autoplay, and then click Properties.

   Note In Windows 2000, the policy setting is named Disable Autoplay.

4. Click Enabled, and then select All drives in the Turn off Autoplay box to disable Autorun on all drives.
5. Click OK to close the Turn off Autoplay Properties dialog box.
6. Restart the computer.

方法二，通过注册表（所有XP系统有效，但是要修改注册表，这个操作有一定风险，请操作前备份好注册表。）：

How to disable all Autorun features in Windows XP Home Edition and other operating systems.

For operating systems that do not include Gpedit.msc, follow these steps:

1. Click Start, click Run, type regedit in the Open box, and then click OK.
   点击”开始“按钮，点击”运行“，在运行对话框中输入”regedit “， 然后点击”确定“。
2. Locate and then click the following entry in the registry:
   HKEY_CURRENT_USER\SOFTWARE\Microsoft\Windows\CurrentVersion\policies\Explorer\NoDriveTypeAutorun
   定位到如下注册表键值：HKEY_CURRENT_USER\SOFTWARE\Microsoft\Windows\CurrentVersion\policies\Explorer\NoDriveTypeAutorun
3. Right-click NoDriveTypeAutoRun, and then click Modify.
   右键选择”NoDriveTypeAutoRun“这个键，然后点击”修改“。
4. In the Value data box, type 0xFF to disable all types of drives. Or, to selectively disable specific drives, use a different value as described in the “How to selectively disable specific Autorun features” section.
   在弹出的键值修改对话框中，把原来的值修改为0xFF。或者用不同的值来有选择性地禁用指定驱动器，详见”How to selectively disable specific Autorun features”章节。
5. Click OK, and then exit Registry Editor.
   点击确定，然后退出注册表编辑器。
6. Restart the computer.
   重启计算机，使设置生效。